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  • Investigating the antibacterial effect of fungal metabolites isolated from fish diet and its effect on E.coli bacteria
  • Issa Gholampour Azizi,1 Narges Asghari Astani,2 Ebrahim Karimian,3,*
    1. Department of Mycology, Faculty of Veterinary Medicine, Islamic Azad University Babol Branch, Babol, Iran
    2. Department of veterinary, Babol Branch, Islamic Azad University, Babol, Iran
    3. Department of veterinary, Babol Branch, Islamic Azad University, Babol, Iran


  • Introduction: In recent years, due to the resistance of pathogens against synthetic antibiotics, the study of natural plants such as essential oils and extracts of plants, animals and minerals has increased. To date, more than 200 secondary metabolites have been reported from endophytic fungi, and some of these secondary metabolites have antimicrobial properties. Therefore, the purpose of this study was to investigate the effect of antifungal metabolites isolated from fish diet and its effect on Escherichia coli bacteria.
  • Methods: For this purpose, samples and secondary metabolites were extracted from the molds in the diet using mycological methods, and the effect of these metabolites was evaluated using the MIC and minimal lethality tests (MBC). Then the obtained data have been subjected to statistical analysis.
  • Results: The results obtained in the present study indicated that the MIC of Aspergillus is 5.00 microliters/ml, the MIC of Aspergillus flavus is 5.0 microliters/ml, the MIC of Penicillium is 5.00 microliters/ml, and the MIC of Rhizopus is 11. 00 microliters per milliliter
  • Conclusion: According to the obtained results, it can be claimed that fungal metabolites can be used as useful antimicrobial chemical compounds to control the growth or even bacterial bacteria
  • Keywords: fungus, secondary metabolite, Escherichia coli, Aspergillus, Penicillium, Rhizopus